Project Description

GP-Cord®

Chlorhexidine Digluconate 7.1% w/v

Description

Chlorhexidine is a very potent, cationic chemoprophylactic agent. It has a broad spectrum action, and is more effective against gm+ve than gm-ve bacteria. It acts by binding to negatively charged bacterial cell wall thereby disrupting membrane integrity and affecting its functions. In high concentrations, chlorhexidine is bactericidal.

Mechanism of Action

  • This preparation contains Chlorhexidine Gluconate and Isopropyl Alcohol Solution
  • Chlorhexidine Gluconate is an antiseptic effective against a wide range of bacteria, yeasts, some other fungi and viruses
  • Chlorhexidine gluconate is most active at neutral or alkaline conditions. Its activity is reduced by the presence of blood or body fluids
  • It binds strongly to skin, mucosa and other tissue and is therefore poorly absorbed.
  • It is bacteriostatic at low concentrations whilst at higher concentrations their activity is rapidly bactericidal
  • They are both active against dermatophytic fungi (including the yeast C. Albicans) and enveloped viruses such as HIV

Indication

  • Application of 7.1% chlorhexidine digluconate (delivering 4% chlorhexidine) to the umbilical cord stump prevents infection and saves lives.

Dosage and Administration

Wash hand with soap and water before/after using GP-Cord. Apply10 ml GP-Cord Solution to umbilcal cord just after birth such as it is completely wet by the applied solution. Don’t wipe out the cord with anything else after using the GP-Cord Solution. Don’t use anything else after using GP-Cord Solution to Cord and keep it dry.

Side effects

Irritative skin reactions to chlorhexidine preparations can occasionally occur. Generalized allergic reactions to chlorhexidine have also been reported but are extremely rare.

 

Precaution

  • Avoid contact with brain, meninges, middle ear
  • Avoid contact with the eyes
  • This preparation is for external use only. Avoid use in body cavities.

Accidental Ingestion

Carry out a stomach lavage with milk, egg white, gelatin or mild soap water.

Storage

Store between 150c – 250c. Keep out of reach of children.

Pack Size

Available in 10 ml LDPE Container

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